Peptides
How Many Peptides Are There
Peptides, short chains of amino acids linked by peptide bonds, play crucial roles in biological processes.
01
Key Facts
- Over 80 FDA-approved peptide drugs are on the market (as of 2023).
- A 10-amino-acid peptide has 20^10 (about 10 trillion) possible combinations.
- Peptide databases include PeptideAtlas and the Antimicrobial Peptide Database.
- Example peptide drugs mentioned: liraglutide, insulin (recombinant), semaglutide, lutathera, and nesiritide.
02
Topics Covered
- The Peptide Universe: Natural and Synthetic
- Biotech-Derived Peptides in Human Medicine (Synthetic Peptides; Recombinant Peptides; Modified Peptides)
- Therapeutic Applications (Metabolic Disorders; Oncology; Cardiovascular Diseases)
- The Challenge of Quantifying Peptides
- The Future of Peptide Therapeutics (AI and Computational Design; Novel Delivery Methods; Personalized Peptide Therapies)
- What's Next
References
- 01insulin — https://www.diabetes.org/healthy-living/medication-treatments/insulin-other-injectables/insulin-basics
- 02"80 FDA-approved peptide drugs" — https://www.frontiersin.org/articles/10.3389/fbioe.2020.00511/full
- 03liraglutide — https://www.ema.europa.eu/en/medicines/human/EPAR/victoza
- 04Insulin — https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287693/
- 05PEGylation — https://www.sciencedirect.com/science/article/pii/S0169409X16301776
- 06semaglutide — https://www.nejm.org/doi/full/10.1056/nejmoa2032183
- 07lutathera — cancer.gov (link truncated in source)
This profile is being expanded — additional sections from the source are still being added.
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